Building a Legacy of Distinction
& Products for Progress

Scientists and industry leaders want efficiency, growth, and quality.
That’s where we come in with technical, highly specialized backgrounds in microbiology and its applications.

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Reducing Unwanted Variables & Damage with Oxyrase

Once we discovered the broad applications and benefits of the Oxyrase Enzyme System®, we knew that we could revolutionize the way anaerobic microbiology, anaerobiosis, and oxidative protection took place. With the ability to grow more robust cultures and eliminate opportunities for oxygen contamination, you can do more of your best work.

Our full team backs all of our products.

You never have to worry about quality, service, or scientific rigor. Oxyrase, Inc. leadership understands that a cutting-edge business in applied microbiology must impress clients on all fronts. We hire the most qualified people in the following areas:

Roles: Quality Control Microbiologist, Quality Control Manager

Specialties
- Oxygen removal efficacy: tests products to ensure they effectively remove oxygen from various environments, essential for anaerobic conditions.
- Microbiological Integrity: ensure products are contaminant-free and support the growth of anaerobic microorganisms, critical for microbiology applications.
- Regulatory Compliance: ensure products meet industry standards and legal requirements.
- Product Consistency and Improvement: maintain consistent product quality across batches and use feedback for enhancements.
- Product Support: ensure all customer feedback is taken into account and action is taken to resolve the issue.

Roles: Production Technician, Production Manager

Manufacturing Plates: Produce OxyPlate™ using the patented OxyDish™ and OxyPRAS Plus® Plate using standard petri dishes in a clean room with high-speed methods.
Quality Control: Ensure all plates are PRAS, adhering to standards for anaerobic microbiology.
Production Scheduling: Plan production in advance, accommodating order changes with appropriate notice.
Custom Manufacturing: Handle contract manufacturing for custom media formulations for clinical anaerobic bacteria isolation.
Incorporation of Oxyrase® Enzyme System: Integrate the enzyme system to ensure anaerobic functionality and extended shelf life.
Clean Room Standards: Maintain sterility during production to ensure plate quality.

Roles: Bioprocessing Technician, Bioprocessing Manager

Production of Oxyrase Enzyme: Cultivate, extract, and purify enzymes for the Oxyrase® Enzyme System.
Optimization of processing: Refine bioprocessing methods to enhance enzyme activity and stability.
Prepare Enzyme products: Formulate enzymes for specific applications like EC-Oxyrase® and Oxyrase® for Broth.

Research and Development Scientist, Research and Development Microbiologist

Develop new Oxyrase Enzyme applications within the microbiology space and other industries such as the food industry
Develop new microbiological plate formulations to meet custom needs of our customers
Validation of new products ensuring they meet high performance standard

Roles: Administrator, Business Services Manager

Order Support: Ensure orders are accurately documented from House and vendor accounts in a timely manner.
Shipping Support: ensure shipping conditions are optimal based on any logistical variables(weather, natural disasters, etc.) and provide updates to customers on order status.
Material Sourcing: Ensure all materials are sourced from reputable and certified manufacturers
Financial Management: Manage receivables and accounts payable, ensuring correct distribution of payments and credits.

Roles: Sales and Marketing Associate

Educate customers on using Oxyrase® Enzyme System products, such as OxyPlate™ and OxyPRAS Plus®, for anaerobic cultivation through demonstrations and training.
Build strategic partnerships with clinical diagnostic labs to integrate Oxyrase’s enzyme-based products into their workflows, expanding market reach.
Address customer complaints promptly, collaborating with technical teams to resolve issues and ensure satisfaction.
Verify that Oxyrase products deliver reliable performance for end users in applications like clinical microbiology and food safety testing.
Respond to complex customer needs by facilitating customized solutions, such as tailored plate formulations, in collaboration with R&D teams.

OUR HISTORY

Founded on Curiosity, Inquiry & Perseverence

The Oxyrase story began in the early 1980s at the Biology Division of Oak Ridge National Laboratory in Tennessee when Dr. Howard Adler and Mr. Weldon Crow were conducting radiobiological experiments. They weren’t looking to discover a novel method of oxygen removal or reduction, but the team observed that membrane fragments derived from Escherichia coli and related microorganisms that they were using in their work could be useful in creating an anaerobic environment when added to any liquid or solid culture media.

Their groundbreaking discovery resulted in the Oxyrase® Enzyme System, which was patented and became the foundation of Oxyrase, Inc. Crow and Adler, along with Adler’s former student and our current president Dr. James C. Copeland, founded the business on April 28, 1987. Turning their academic work into a business venture has served research in higher education, medical testing and research labs, and the food industry. Over the years, the Oxyrase® Enzyme System has provided people with a solution to their application needs. In addition to its use in applied microbiology, the Oxyrase® Enzyme System has aided in advancing scientific inquiry and study. Many papers published in scientific journals have covered the importance of Oxyrase’s stimulative effects on the growth of anaerobic pathogens and starter cultures that reduce fermentation time in food processes. Several other uses of Oxyrase have been and continue to be explored today.

The love of science and our incurable curiosity has afforded us the opportunity to reach diverse groups and contribute to important research across the globe. We strive to keep our place as pioneers in the business of microbiological products.

Copeland’s Leadership

Our foundational intellectual interest and commitment to excellence at Oxyrase, Inc. continues under Copeland’s leadership. With Adler and Mr. Gerald Spady, he created the innovative OxyDish™ in the late 1990s. Since then, new applications for the system have been under development, keeping in mind the importance of making cost effective methods for creating and controlling anaerobic environments—for whatever reasons they are needed.

Copeland has trained in molecular genetics as an American Cancer Society Postdoctoral Fellow at the Albert Einstein College of Medicine in New York City. He conducted research in areas of microbial genetics and regulatory mechanisms as a staff scientist in the Biology Division at Argonne National Laboratory. Copeland was also a tenured faculty member in the Department of Microbiology at The Ohio State University in Columbus, Ohio. He became Director of Research and Development, Biotechnology at CPC International in Argo, Illinois.

Enough from us.
What do our clients say?

“Oxyrase media has great out-dates. Media arrives promptly and as ordered. Their sales staff and technical staff have always been helpful and able to answer our questions. We have been using this company’s anaerobic media for several years and are perfectly satisfied.”

— Microbiology/Virology Supervisor at Dayton Children’s Hospital

“My student and I were conducting some independent research with pre dental students. One of them wanted to see if an organism failed to grow without oxygen present. She couldn’t believe what a difference Oxyrase® for Broth makes. She thought there would be at least a little growth, but there was nothing! Zip! We now call Oxyrase® for Broth our ‘Magic Drops.’”

— Professor from a Large University Research Center

“In my opinion, these plates save labor because there is efficiency in being able to have the aerobic and anaerobic plates inoculated and incubated together. Plus, if an OxyPlate™ fails, it only impacts one plate, which eliminates the work of having to take time to load and unload a chamber or jars, which is often not near the setup area. Also, there is less delay in the plates achieving anaerobiosis.”

— Diagnostic tech from a Large Medical Laboratory in New England

Building a Legacy of Distinction & Products for Progress